Chromosome Duplication in Saccharomyces cerevisiae

Chromosome Duplication in Saccharomyces cerevisiae

The accurate and complete replication of genomic DNA is essential for all life. In eukaryotic cells, the assembly of the multi-enzyme replisomes that perform replication is divided into stages that occur at distinct phases of the cell cycle. Replicative DNA helicases are loaded around origins of DNA replication exclusively during G1 phase. The loaded helicases are then activated during S phase ...

Duplication processes in Saccharomyces cerevisiae haploid strains

Duplication is thought to be one of the main processes providing a substrate on which the effects of evolution are visible. The mechanisms underlying this chromosomal rearrangement were investigated here in the yeast Saccharomyces cerevisiae. Spontaneous revertants containing a duplication event were selected and analyzed. In addition to the single gene duplication described in a previous study...

NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae

A mutant, ndc10-1, was isolated by anti-tubulin staining of temperature-sensitive mutant banks of budding yeast. ndc10-1 has a defect chromosome segregation since chromosomes remains at one pole of the anaphase spindle. This produces one polyploid cell and one aploid cell, each containing a spindle pole body (SPD. NDC10 was cloned and sequenced and is identical to CBF2 (Jiang, W., J. Lechnermn ...

NDCIO: A Gene Involved in Chromosome Segregation in Saccharomyces cerevisiae

A mutant, ndclO-1, was isolated by antitubulin staining of temperature-sensitive mutant banks of budding yeast, ndclO-1 has a defect in chromosome segregation since chromosomes remain at one pole of the anaphase spindle. This produces one polyploid cell and one aploid cell, each containing a spindle pole body (SPB). NDCIO was cloned and sequenced and is identical to CBF2 (Jiang, W., J. Lechner,...

The Role of H2A.Z in Chromosome Segregation in Saccharomyces cerevisiae